Procedure 2A

Procedure: Project 2 Reaction A

1. In a 25 mL round bottom flask, combine a small stir bar, p-methoxyacetophenone (0.15 g) and glacial acetic acid (1.0 mL).

2. While stirring the mixture on a stir plate, add household bleach (2.0 mL) dropwise.

3. Stir the resulting solution at room temperature for 30 min.

4. After the reaction period, add distilled water (5 mL) to the reaction flask. A solid should precipitate.

5. Collect the precipitate by vacuum filtration and wash it with additional distilled water.

6. After drying the solid on the Buchner funnel for at least 45 min, determine the mass of the collected solid.

7. Analyze the product by GC-MS: In a vial, dissolve a half-rice-grain sized amount of solid in ~3 mL ethyl acetate. Your instructor will direct you on the use of the instrument.

8. Analyze the product by IR.

9. Analyze the product by NMR: Follow the instructions at the NMR preparations station to prepare an NMR sample in deuterated chloroform (CDCl3).

NOTES

1. Fully prepare your Lab Notebook according to the guidelines before entering the lab.

2.  To calculate the amount of NaOCl used in the reaction, you may assume that the commercial bleach solution you will use is 6.0% NaOCl by mass. (This means that each 100 mL of solution contains 6.0 g of NaOCl).

3. You must complete the Project 2A Prelab Quiz before entering the lab to perform this procedure.