{"id":32,"date":"2021-09-29T11:34:30","date_gmt":"2021-09-29T15:34:30","guid":{"rendered":"https:\/\/blog.richmond.edu\/shugruelab\/?page_id=32"},"modified":"2025-11-27T21:23:07","modified_gmt":"2025-11-28T02:23:07","slug":"publications","status":"publish","type":"page","link":"https:\/\/blog.richmond.edu\/shugruelab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"
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Publications at the University of Richmond<\/strong><\/h3>\n

17. Rubio, P. R.(+); Clausen, G. A.(+); Ruighaver, Z. D.(+); Dalton, A. F.; Blobe, J. P.; Moore, A. L.; Shugrue, C. R.* Benzothiazole Sulfones as a Tool for Peptide Modification and Cleavage. Bioorg. Med. Chem<\/em>. 2025<\/strong>, 103<\/em>, 118500.\u00a0Link<\/a><\/p>\n

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16.\u00a0 Watts, A. W.(+); Hughes, C. J.(+); Clausen, G. A.(+); Yanar, P.; Wolff, E. J.; Rubio, P. R.; Stuart, N. M.; Shugrue, C. R. Electron-rich anilines as cleavable linkers for peptides. Bioorg. Chem<\/em>. 2025<\/strong>, 154<\/em>, 108084.\u00a0Link<\/a><\/p>\n

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15.\u00a0 \u00a0Taggart, E. L.(+); Wolff, E. J.(+); Yanar, P.; Blobe, J. P.; Shugrue, C. R. Development of an oxazole-based cleavable linker for peptides. Bioorg. Med. Chem.<\/em> 2024<\/strong>, 102<\/em>, 117663. Link<\/a>.<\/p>\n

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Postdoctoral Publications from Massachusetts Institute of Technology (with Prof. Bradley Pentelute):<\/strong><\/h3>\n

14.\u00a0 \u00a0Tuan, S.; Dieppa-Matos, D.; Zhang, C.; Shugrue, C. R.; Dai, P.; Truex, N.; Zhang, G.; Loas, A.; Pentelute, B. L. A reactive peptide interface for site-selective cysteine bioconjugation. Chem. Commun.<\/em> 2021<\/strong>, 57<\/em>, 3227\u20133230. Link<\/a>.<\/p>\n

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13.\u00a0 \u00a0Pomplun, S. J.(+); Shugrue, C. R.(+); Schmitt, A. M.<\/span>; Schissel, C. K.; Farquhar, C. E.; Pentelute, B. L. Secondary Amino Alcohols: Traceless Cleavable Linkers for Use in Affinity Capture and Release. Angew. Chem. Int. Ed<\/em>. 2020<\/strong>, 59<\/em>, 11566\u201311572. (+ co-first authors). Link<\/a>.<\/p>\n

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G<\/strong>raduate Publications from Yale University (with Prof. Scott Miller):<\/strong><\/h3>\n

12.\u00a0 \u00a0Metrano, A. J.; Chinn, A. J.; Shugrue, C. R.; Stone, E. A.; Kim, B.; Miller, S. J. Asymmetric Catalysis Mediated by Synthetic Peptides, Version 2.0: Expansion of Scope and Mechanisms. Chem. Rev<\/em>. 2020<\/strong>, 120<\/em>, 11479\u201311615. Link<\/a>.<\/p>\n

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11.\u00a0 \u00a0Dardir, A. H.; Hazari, N.; Miller, S. J.; Shugrue, C. R. Palladium-Catalyzed Suzuki-Miyaura Reactions of Aspartic Acid Derived Phenyl Esters. Org. Lett<\/em>. 2019<\/strong>, 21<\/em>, 5762\u20135766. Link<\/a>. Highlighted in<\/strong><\/em>: Synfacts<\/em> 2019<\/strong>, 15<\/em>, 1324. Link<\/a>.<\/p>\n

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10.\u00a0 \u00a0Shugrue, C. R.; Sculimbrene, B. R.; Jarvo, E. R.; Mercado, B. W.; Miller, S. J. Outer-Sphere Control for Divergent Multicatalysis with Common Catalytic Moieties. J. Org. Chem<\/em>. 2019<\/strong>, 84<\/em>, 1664\u20131672. Link<\/a>.<\/p>\n

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9.\u00a0 \u00a0Featherston, A. L.; Shugrue, C. R.; Mercado, B. Q; Miller, S. J. Phosphothreonine (pThr)\u2013Based Multifunctional Peptide Catalysis for Asymmetric Baeyer\u2013Villiger Oxidations of Cyclobutanones. ACS Catal.<\/em>\u00a02019<\/strong>, 9<\/em>, 242\u2013252. Link<\/a>. Highlighted in<\/strong><\/em>: Synfacts<\/em> 2019<\/strong>, 15<\/em>, 0303. Link<\/a>.<\/p>\n

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8.\u00a0 \u00a0Shugrue, C. R.; Featherston, A. L.; Lackner, R. M.<\/span>; Lin, A.<\/span>; Miller, S. J. Divergent Stereoselectivity in Phosphothreonine (pThr)-Catalyzed Reductive Aminations of 3-Amidocyclohexanones. J. Org. Chem<\/em>. 2018<\/strong>, 83<\/em>, 4491\u20134504. Link<\/a>.<\/p>\n

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7.\u00a0 \u00a0Shugrue, C. R.; Miller, S. J. Applications of Non-Enzymatic Catalysts to the Alteration of Natural Products. Chem. Rev. 2017, 117, 11894\u201311951. Special Issue<\/strong><\/em>: Natural Product Synthesis<\/em>. Link<\/a>.<\/p>\n

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6.\u00a0 \u00a0Alford, J. A.; Abascal, N. C.; Shugrue, C. R.; Colvin, S. M.; Romney, D. K. Aspartyl Oxidation Catalysts that Dial In Functional Group Selectivity, along with Regio- and Stereoselectivity. ACS Cent. Sci<\/em>. 2016<\/strong>, 2<\/em>, 733\u2013739. Link<\/a>.<\/p>\n

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5.\u00a0 \u00a0Shugrue, C. R.; Miller, S. J. Phosphothreonine as a Catalytic Residue in Peptide-Mediated Asymmetric Transfer Hydrogenations of 8-Aminoquinolines. Angew. Chem. Int. Ed<\/em>. 2015<\/strong>, 54<\/em>, 11173\u201311176. Link<\/a>.<\/p>\n

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Undergraduate Publications from Holy Cross and UT Austin (with Prof. Brian Linton & Prof. Stephen Martin):<\/strong><\/h3>\n

4.\u00a0 \u00a0Klosowski, D. W.; Hethcox, J. C.; Paull, D. H.; Fang, C.; Donald, J. R.; Shugrue, C. R.<\/span>; Pansick, A. D.; Martin, S. F. Enantioselective Halolactonization Reactions using a BINOL-derived Bifunctional Catalyst: Methodology, Diversification, and Applications. J. Org. Chem<\/em>. 2018<\/strong>, 83<\/em>, 5954\u20135968. Link<\/a>. Highlighted in<\/strong><\/em>: Synfacts<\/em> 2018<\/strong>, 14<\/em>, 0790. Link<\/a>.<\/p>\n

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3.\u00a0 \u00a0Shugrue, C. R.<\/span>; DeFrancisco, J. R.<\/span>; Metrano, A. J.<\/span>; Brink, B. B.<\/span>; Nomoto, R. S.<\/span>; Linton, B. R. Detection of Weak Hydrogen Bonding to Fluoro and Nitro Groups in Solution using H\/D Exchange. Org. Biomol. Chem<\/em>. 2016<\/strong>, 14<\/em>, 2223\u20132227. Link<\/a>.<\/p>\n

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2.\u00a0 \u00a0Shugrue, C. R.<\/span>; Mentzen, H. H.; Linton, B. R. A colorful solubility exercise for organic chemistry. J. Chem. Ed<\/em>. 2014<\/strong>, 92<\/em>, 135\u2013138. Link<\/a>. Cover Article<\/strong><\/em>. Link<\/a>.<\/p>\n

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1.\u00a0 \u00a0Fang, C.; Paull, D. H.; Hethcox, C. J.; Shugrue, C. R<\/span>.; Martin, S. F. Enantioselective Iodolactonization of Disubstituted Olefinic Acids Using a Bifunctional Catalyst. Org. Lett<\/em>. 2012<\/strong>, 14<\/em>, 6290\u20136293. Link<\/a>.<\/p>\n

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Publications at the University of Richmond 17. Rubio, P. R.(+); Clausen, G. A.(+); Ruighaver, Z. D.(+); Dalton, A. F.; Blobe,<\/p>\n","protected":false},"author":5323,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"coauthors":[196374],"class_list":["post-32","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blog.richmond.edu\/shugruelab\/wp-json\/wp\/v2\/pages\/32","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.richmond.edu\/shugruelab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blog.richmond.edu\/shugruelab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blog.richmond.edu\/shugruelab\/wp-json\/wp\/v2\/users\/5323"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.richmond.edu\/shugruelab\/wp-json\/wp\/v2\/comments?post=32"}],"version-history":[{"count":13,"href":"https:\/\/blog.richmond.edu\/shugruelab\/wp-json\/wp\/v2\/pages\/32\/revisions"}],"predecessor-version":[{"id":290,"href":"https:\/\/blog.richmond.edu\/shugruelab\/wp-json\/wp\/v2\/pages\/32\/revisions\/290"}],"wp:attachment":[{"href":"https:\/\/blog.richmond.edu\/shugruelab\/wp-json\/wp\/v2\/media?parent=32"}],"wp:term":[{"taxonomy":"author","embeddable":true,"href":"https:\/\/blog.richmond.edu\/shugruelab\/wp-json\/wp\/v2\/coauthors?post=32"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}