{"id":303,"date":"2017-01-27T18:00:35","date_gmt":"2017-01-27T22:00:35","guid":{"rendered":"http:\/\/blog.richmond.edu\/pollocklab\/?p=303"},"modified":"2017-01-27T18:01:05","modified_gmt":"2017-01-27T22:01:05","slug":"hemoglobin-lecture","status":"publish","type":"post","link":"https:\/\/blog.richmond.edu\/pollocklab\/2017\/01\/27\/hemoglobin-lecture\/","title":{"rendered":"Hemoglobin Lecture"},"content":{"rendered":"<p>[et_pb_section admin_label=&#8221;section&#8221;][et_pb_row admin_label=&#8221;row&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_text admin_label=&#8221;Text&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;justified&#8221; text_text_color=&#8221;#000000&#8243; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; text_font=&#8221;Droid Serif||||&#8221;]<\/p>\n<p>If you have ever heard me talk about my biochemistry course, you have probably heard me talk about hemoglobin. Every semester I teach this course, I geek out to my students about this amazing protein. My voice gets more high pitched, I throw my hands in the air, and I exclaim &#8220;isn&#8217;t this so cool?!?&#8221; Inevitably, maybe because it is a morning class or maybe because science doesn&#8217;t make them nearly as excited as it makes me, the majority of them look at me like I&#8217;m crazy. But I&#8217;m holding my position, I will continue to promote the impressive biochemical functions of\u00a0hemoglobin in hopes that at least one or two will join me in my enthusiasm.<\/p>\n<p>Now you are all asking: Why is hemoglobin so amazing? Let me count the ways&#8230;<\/p>\n<ol>\n<li>The cooperativity between the protein subunits allows hemoglobin to pick up oxygen in our lungs and deliver it to our tissues. <strong>**This is why we can breathe and generate energy to fuel our cells**<\/strong><\/li>\n<li>The binding of BPG facilitates the release of oxygen, and therefore the expression of BPG increases at higher altitudes to help you release more oxygen at lower air concentrations. <strong>**This is why runners train at higher altitudes**<\/strong><\/li>\n<li>The subunits of fetal hemoglobin are different than the subunits of adult hemoglobin so that they have a lower affinity for BPG so that oxygen can be transferred from the mother&#8217;s blood to the fetus&#8217;s blood. <strong>**This is why you should always be nice to pregnant ladies; the fetus is stealing their oxygen**<\/strong><\/li>\n<li>Carbon monoxide binds more tightly to hemoglobin than oxygen. <strong>**This is why you should not smoke and why we need to care about air pollution**<\/strong><\/li>\n<\/ol>\n<p>So breathe deep, fill your lungs with oxygen, imagine all the binding sites of your hemoglobin picking up oxygen, and run\u00a0off to make the\u00a0world a better place. Biochemistry, and the amazing hemoglobin, is allowing you to do it!<\/p>\n<p>~jap<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you have ever heard me talk about my biochemistry course, you have probably heard me talk about hemoglobin. Every semester I teach this course, I geek out to my students about this amazing protein. My voice gets more high pitched, I throw my hands in the air, and I exclaim &#8220;isn&#8217;t this so cool?!?&#8221; [&hellip;]<\/p>\n","protected":false},"author":2906,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[795,33],"tags":[],"class_list":["post-303","post","type-post","status-publish","format-standard","hentry","category-blog","category-teaching"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/posts\/303","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/users\/2906"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/comments?post=303"}],"version-history":[{"count":0,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/posts\/303\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/media?parent=303"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/categories?post=303"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/tags?post=303"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}