{"id":1094,"date":"2021-01-26T16:20:50","date_gmt":"2021-01-26T20:20:50","guid":{"rendered":"http:\/\/blog.richmond.edu\/pollocklab\/?p=1094"},"modified":"2021-01-26T16:20:50","modified_gmt":"2021-01-26T20:20:50","slug":"a-new-memo-publication","status":"publish","type":"post","link":"https:\/\/blog.richmond.edu\/pollocklab\/2021\/01\/26\/a-new-memo-publication\/","title":{"rendered":"A new MEMO publication"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243;][et_pb_row][et_pb_column type=&#8221;4_4&#8243;][et_pb_text _builder_version=&#8221;4.4.4&#8243; text_text_shadow_horizontal_length=&#8221;text_text_shadow_style,%91object Object%93&#8243; text_text_shadow_horizontal_length_tablet=&#8221;0px&#8221; text_text_shadow_vertical_length=&#8221;text_text_shadow_style,%91object Object%93&#8243; text_text_shadow_vertical_length_tablet=&#8221;0px&#8221; text_text_shadow_blur_strength=&#8221;text_text_shadow_style,%91object Object%93&#8243; text_text_shadow_blur_strength_tablet=&#8221;1px&#8221; 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header_3_text_shadow_blur_strength_tablet=&#8221;1px&#8221; header_4_text_shadow_horizontal_length=&#8221;header_4_text_shadow_style,%91object Object%93&#8243; header_4_text_shadow_horizontal_length_tablet=&#8221;0px&#8221; header_4_text_shadow_vertical_length=&#8221;header_4_text_shadow_style,%91object Object%93&#8243; header_4_text_shadow_vertical_length_tablet=&#8221;0px&#8221; header_4_text_shadow_blur_strength=&#8221;header_4_text_shadow_style,%91object Object%93&#8243; header_4_text_shadow_blur_strength_tablet=&#8221;1px&#8221; header_5_text_shadow_horizontal_length=&#8221;header_5_text_shadow_style,%91object Object%93&#8243; header_5_text_shadow_horizontal_length_tablet=&#8221;0px&#8221; header_5_text_shadow_vertical_length=&#8221;header_5_text_shadow_style,%91object Object%93&#8243; header_5_text_shadow_vertical_length_tablet=&#8221;0px&#8221; header_5_text_shadow_blur_strength=&#8221;header_5_text_shadow_style,%91object Object%93&#8243; header_5_text_shadow_blur_strength_tablet=&#8221;1px&#8221; header_6_text_shadow_horizontal_length=&#8221;header_6_text_shadow_style,%91object Object%93&#8243; header_6_text_shadow_horizontal_length_tablet=&#8221;0px&#8221; header_6_text_shadow_vertical_length=&#8221;header_6_text_shadow_style,%91object Object%93&#8243; header_6_text_shadow_vertical_length_tablet=&#8221;0px&#8221; header_6_text_shadow_blur_strength=&#8221;header_6_text_shadow_style,%91object Object%93&#8243; header_6_text_shadow_blur_strength_tablet=&#8221;1px&#8221; box_shadow_horizontal_tablet=&#8221;0px&#8221; box_shadow_vertical_tablet=&#8221;0px&#8221; box_shadow_blur_tablet=&#8221;40px&#8221; box_shadow_spread_tablet=&#8221;0px&#8221; vertical_offset_tablet=&#8221;0&#8243; horizontal_offset_tablet=&#8221;0&#8243; z_index_tablet=&#8221;0&#8243;]<\/p>\n<p>I would say the latest publication from the lab (accepted in mid-December) was a long time coming. Kristen started the virtual screening when she was working as a post-bac in spring 2018. Then Courtney took a hold of the screening and was a machine in her 384-well plate fluorescence polarization assay. Cassidy rocked the cell experiments that Kristen pioneered. And our computational collaborators &#8211; Dr. Carol Parish, Justin Airas, and Alexis Blake &#8211; assisted in making it a beautiful story.\u00a0<\/p>\n<p>This was a project I had in my mind when the lab first started working on MEMO1. We established protocols and built biophysical assays and told a <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.8b00582\">wonderful story<\/a> about MEMO1 interactions a couple of years ago. However, this paper takes it a bit further and identifies the <em><strong>very first small molecule inhibitors of the protein<\/strong><\/em>. I think it is pretty impressive. And it was done by an amazing team of undergraduate students. I am constantly amazed at their scientific capabilities. Good work to everyone!<\/p>\n<p>See the beautifully formatted manuscript <a href=\"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/cmdc.202000797\">here<\/a>.\u00a0<\/p>\n<p>~jap<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p><div class=\"et_pb_row et_pb_row_0 et_pb_row_empty\">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div> I would say the latest publication from the lab (accepted in mid-December) was a long time coming. Kristen started the virtual screening when she was working as a post-bac in spring 2018. Then Courtney took a hold of the screening and was a machine in her 384-well plate fluorescence polarization assay. Cassidy rocked the [&hellip;]<\/p>\n","protected":false},"author":2906,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[795,659,508,35898],"tags":[],"class_list":["post-1094","post","type-post","status-publish","format-standard","hentry","category-blog","category-publications","category-research","category-students"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/posts\/1094","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/users\/2906"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/comments?post=1094"}],"version-history":[{"count":1,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/posts\/1094\/revisions"}],"predecessor-version":[{"id":1095,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/posts\/1094\/revisions\/1095"}],"wp:attachment":[{"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/media?parent=1094"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/categories?post=1094"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.richmond.edu\/pollocklab\/wp-json\/wp\/v2\/tags?post=1094"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}