{"id":758,"date":"2022-05-27T11:27:29","date_gmt":"2022-05-27T15:27:29","guid":{"rendered":"https:\/\/blog.richmond.edu\/chem205l\/?page_id=758"},"modified":"2022-05-27T11:27:29","modified_gmt":"2022-05-27T15:27:29","slug":"project-2-procedure-f22","status":"publish","type":"page","link":"https:\/\/blog.richmond.edu\/chem205l\/project-2-procedure-f22\/","title":{"rendered":"Project 2 Procedure F22"},"content":{"rendered":"

THE REACTION<\/strong><\/p>\n

1. Dissolve trimyristin (0.5 g) in methanol (12 mL) in a 50 mL round bottom flask.<\/p>\n

2. Add concentrated sulfuric acid (250 \u03bcL) to the flask, and heat the solution to reflux for 1 hour.<\/p>\n

THE WORKUP<\/strong><\/p>\n

3. Cool the solution to room temperature and then pour it into 25 mL distilled water in a separatory funnel.<\/p>\n

4. Extract<\/a> the mixture with 25 mL ethyl acetate, and separate the two layers. Transfer the organic layer to a 50 mL Erlenmeyer flask.<\/p>\n

5. Return the aqueous layer to the separatory funnel and extract it with a fresh 25 mL portion of ethyl acetate.<\/p>\n

6. Remove the aqueous layer, and return the first organic layer to the funnel.<\/p>\n

7. Wash the combined organic layers with brine (saturated NaCl). Remove the aqueous solution, and transfer the organic layer to a 125 mL Erlenmeyer flask.<\/p>\n

8. Dry<\/a> the organic layer over sodium sulfate.<\/p>\n

9. Gravity filter<\/a> the mixture into a preweighed<\/strong> 100 mL round bottom flask in order to remove the sodium sulfate. (Note: Pre-folded filter paper is available to you in the lab.)<\/p>\n

10. Remove the solvent by rotary evaporation<\/span><\/a> to give a clear oil. Determine the mass of the product.<\/p>\n

PRODUCT ANALYSIS<\/strong><\/p>\n

11. Prepare a GC-MS sample by dissolving a single drop of your product into 2 mL ethyl acetate in a test tube. Your instructor\/TA will assist you in obtaining the GC-MS data.<\/p>\n

12. Obtain an IR spectrum of your product.<\/p>\n

13. Save the remaining product in a test tube at your lab station.<\/p>\n","protected":false},"excerpt":{"rendered":"

THE REACTION 1. Dissolve trimyristin (0.5 g) in methanol (12 mL) in a 50 mL round bottom flask. 2. Add concentrated sulfuric acid (250 \u03bcL) to the flask, and heat the solution to reflux for 1 hour. THE WORKUP 3. … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":5206,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"coauthors":[175315],"class_list":["post-758","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blog.richmond.edu\/chem205l\/wp-json\/wp\/v2\/pages\/758","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.richmond.edu\/chem205l\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blog.richmond.edu\/chem205l\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blog.richmond.edu\/chem205l\/wp-json\/wp\/v2\/users\/5206"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.richmond.edu\/chem205l\/wp-json\/wp\/v2\/comments?post=758"}],"version-history":[{"count":1,"href":"https:\/\/blog.richmond.edu\/chem205l\/wp-json\/wp\/v2\/pages\/758\/revisions"}],"predecessor-version":[{"id":759,"href":"https:\/\/blog.richmond.edu\/chem205l\/wp-json\/wp\/v2\/pages\/758\/revisions\/759"}],"wp:attachment":[{"href":"https:\/\/blog.richmond.edu\/chem205l\/wp-json\/wp\/v2\/media?parent=758"}],"wp:term":[{"taxonomy":"author","embeddable":true,"href":"https:\/\/blog.richmond.edu\/chem205l\/wp-json\/wp\/v2\/coauthors?post=758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}