NOTE: If the sample of carvone you isolated in Project 3 was relatively pure, you may use it for Project 4. If your carvone sample was impure, or if you did not isolate enough material, use the stock of carvone supplied in the lab.<\/p>\n
1. In a 25 mL round bottom flask, add ~0.5 g carvone.<\/p>\n
2. Add 5 mL of 6 M HCl and a small stir bar to the flask, attach a reflux condenser, and heat the reaction mixture to a gentle reflux<\/a> <\/span>for 1 hour.<\/p>\n 3. Remove the reaction flask from the heat and allow the reaction mixture to cool to room temperature.<\/p>\n 4. Extract<\/a><\/span> the mixture with ethyl acetate (2 \u00d7 10 mL), and then wash the combined organic layers with brine.<\/p>\n 5. Dry<\/a><\/span> the combined organic layers with sodium sulfate, gravity filter<\/a> <\/span>the mixture, and remove the solvent using rotary evaporation.<\/p>\n 6. Determine the mass of your product.<\/p>\n 7. Obtain 1<\/sup>H NMR, \u00b9\u00b3C NMR, IR and GC-MS data.<\/p>\n 8. Your product can be deposited in the collection bottle provided in the lab.<\/p>\n","protected":false},"excerpt":{"rendered":" NOTE: If the sample of carvone you isolated in Project 3 was relatively pure, you may use it for Project 4. If your carvone sample was impure, or if you did not isolate enough material, use the stock of carvone … Continue reading